Table 1. Effect of GDP-locked and GTP-locked Rags on membrane association of SPG15-GFP and mTOR.

	SPG15		mTOR
Rag	fed	starved	fed	starved
Control	+	+++	+++	−
RagAGDP	nc	nc	↓hi	nc
RagAGTP	↓↓	↓↓	nc	↑↑↑
RagBGDP	nc	nc	nc	nc
RagBGTP	↓↓	↓↓	nc	↑hi
RagCGDP	↑↑↑	nc	↑↑	↑↑↑
RagCGTP	nc*	nc*	nc*	nc*
RagDGDP	nc	nc	↑	↑↑↑
RagDGTP	nc	nc	nc	nc

+ and −, membrane association in control cells; nc, no change compared to control; ↓↑, change in membrane association; hi, only in high expressers; *, poor expression levels.