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Severity of aneurysm development in mouse cerebral aneurysm model. (A) Anti-CXCL1 treated mice did not develop aneurysms at 2 weeks compared with IgG treated mice. Scale bar=2 mm. (B) Aneurysm development in the IgG control group displayed varying levels of severity that were significantly different from anti-CXCL1 treated mice when scored using (C) the 5 point grading scale (circle=aneurysm, dotted circle=ruptured aneurysm) (p=0.0046 by Mann–Whitney test, *p<0.05).
