Table 2:
Virus | WPV1 (PIR = 1/200) | WPV3 (PIR = 1/1000) | ||||||
---|---|---|---|---|---|---|---|---|
POE | 100% | 100% | ||||||
Metric | CNCx% | TUCx% | CNCx% | TUCx% | ||||
x% | 95% | 99% | 95% | 99% | 95% | 99% | 95% | 99% |
DEFP values assuming perfect AFP surveillance | ||||||||
Scenario 1 | 1.33 | 1.83 | 0.97 | 1.38 | 1.75 | 2.50 | 1.41 | 1.76 |
Scenario 2 | 1.58 | 1.92 | 0.98 | 1.34 | ||||
DEFP values assuming less than perfect AFP surveillance, lower bound | ||||||||
Scenario 1 | 3.00 | 3.75 | 2.75 | 3.69 | 3.08 | 6.50 | 2.21 | 6.49 |
Scenario 2 | 3.42 | 3.75 | 3.35 | 3.72 | ||||
DEFP values assuming less than perfect AFP surveillance, accessibility factor | ||||||||
Scenario 1 | 1.92 | 2.25 | 1.14 | 1.58 | 2.42 | 4.42 | 1.52 | 3.99 |
Scenario 2 | 2.08 | 2.50 | 1.11 | 1.69 | ||||
DEFP values assuming less than perfect AFP surveillance, upper bound | ||||||||
Scenario 1 | 1.75 | 2.08 | 1.07 | 1.58 | 2.25 | 3.42 | 1.48 | 3.18 |
Scenario 2 | 2.00 | 2.33 | 1.05 | 1.46 |
Scenario 1 assumes sufficient indirect vaccination introductions into the isolated subpopulations to eliminate undetected WPV1 transmission after the outbreak detected in 2016; Scenario 2 assumes insufficient indirect vaccination introductions into isolated subpopulations to eliminate undetected WPV1 transmission through the end of 2019.
Abbreviations: AFP, acute flaccid paralysis; CNCx%, DEFP at which the confidence about no circulation exceeds x%; DEFP, detected-event-free period; PIR, paralysis-to-infection ratio; POE, probability of eradication; TUCx%, the xth percentile of the distribution of the times of undetected circulation after the last detected-event (for those iterations in which extinction occurs); WPV(1,3), wild poliovirus (serotypes 1,3).