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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Cell Syst. 2020 Sep 10;11(3):215–228.e5. doi: 10.1016/j.cels.2020.08.002

Figure 6. In Silico T Cell Circuit Design: Expansive Search and Provided Resources.

Figure 6.

(A) In silico analysis of tumor-versus-normal expression data can be used to identify discriminatory antigen patterns. These potential antigen signatures can then be used as the basis for synthetic biology engineering of precision therapeutic T cells.

(B) We have generated an interactive webserver that allows public access to the datasets used in this paper; allowing users to identify potential discriminatory singlets, doublets, and triplets for cancer detection in the future (antigen.princeton.edu).