Table 1.
“Clinical” Antigens Currently under Investigation as CAR Targets in Clinical Trials as Identified from Clinicaltrials.gov
| Antigen | Clinical Trial |
|---|---|
| AXL | NCT03393936 |
| CAIX-2 | DDHK97-29 |
| CD133 | NCT02541370 |
| CD137 | NCT02862704 |
| CD147 | NCT04045847 |
| CD70 | NCT02830724 |
| CD80 | NCT03198052 |
| CEA | NCT01373047 |
| CLDN18 | NCT03159819 |
| EGFR | NCT02331693 |
| EpCAM | NCT02915445 |
| EPHA2 | NCT03423992 |
| FAP | NCT01722149 |
| FOLR1 | NCT00019136 |
| GD2 | NCT00085930 |
| GPC3 | NCT02959151 |
| IL13RA2 | NCT00730613 |
| HER2 | NCT02442297 |
| L1CAM | NCT02311621 |
| MSLN | NCT02930993 |
| MET | NCT01837602 |
| MUC1 | NCT02617134 |
| MUC16 | NCT02498912 |
| PD-L1 | NCT0330834 |
| PSCA | NCT02744287 |
| PSMA | NCT01929239 |
| ROR1 | NCT02706392 |
| ROR2 | NCT03393936 |
| VEGFR2 | NCT01218867 |