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. 2021 Jan 19;21:31. doi: 10.1186/s12890-021-01396-8

Table 1.

Peripheral blood neutrophils from mice infected with A. fumigatus

Group Neutrophils (mean × 103/µL ± SD)a
Day 1 post-infection Day 3 post-infection
Control 0.95 ± 0.29 0.88 ± 0.1
Immunocompetent/exposed 0.88 ± 0.19 0.94 ± 0.67
CTX-IPA 0.01 ± 0.01*,# 0.02 ± 0.01*,#
HC-IPA 1.43 ± 0.77 2.55 ± 1.68

Treatments were as follows: cyclophosphamide (250 mg/kg) intraperitoneally on the day before the 1st and 3rd challenges (CTX-IPA); hydrocortisone (62.5 mg/kg) subcutaneously every other day, from 5 days before infection (d-5) to the day after infection (d + 1)(HC-IPA);

Mice were infected intranasally with 50 μL (1 × 108conidia/mL) of A. fumigatus spore suspension. The groups of control received 50 μL of phosphate buffer saline (PBS). Blood samples were collected from four mice per group at the indicated days post-infection

aSD, standard deviation; *p < 0.05, compared with the control group. #p < 0.05, compared with the immunocompetent/exposed group