Table 2.
Fungal burden of organs in mice infected with A. fumigatus
Group | Fungal burden of organs(mean log10 CFU/g ± SD)a | ||
---|---|---|---|
Lung | Brain | Kidneys | |
Control | None | None | None |
Immunocompetent/exposed | None | None | None |
CTX-IPA | 4.19 ± 0.35* | 2.35 ± 0.33 | 1.60 ± 0.69 |
HC-IPA | 3.27 ± 0.41* | None | None |
Mice were inoculated intranasally with 50 μL (1 × 108 conidia/mL) of A. fumigatus spore suspension in IPA group and immunocompetent/exposed group. The groups of control received 50 μL of phosphate buffer saline (PBS). Tissue samples were collected from four mice per group on day 3 post-infection. Fungal burden in mice was measured 3 day after infection. Fungal burden was expressed as log10 CFU/g of tissue
aCFU, colony-forming unit; SD, standard deviation; *p < 0.05, CTX-IPA group versus HC-IPA group