Fig. 3.

Motor coordination deficits in Shank3 mice. Time to traverse the beam was only slightly affected in the last section of the beam, and which is the narrower, in Shank3 ΔC/ΔC females. This is indicative of motor coordination deficits. All data are expressed as means ± SEM. One-way ANOVA followed by Tukey’s multiple analysis was performed (*p < 0.05, **p < 0.01, ***p < 0.001) WT males n = 10; Shank3+/ΔC males n = 20; Shank3 ΔC/ΔC males, n = 14; WT females n = 14; Shank3+/ΔC females n = 17; Shank3 ΔC/ΔC females, n = 12