Figure 8.

The effect of topical mGluR2/3 agonist LY354740 application on spontaneous firing rates. A, Spontaneous activity significantly increased in neurons assigned to the drug effect group (n = 20). B, Spontaneous activity did not significantly change in neurons assigned to the no drug effect group (n = 11). Each neuron’s pre-drug and post-drug means are connected by gray lines; population data are summarized with boxplots (the plot presents rank-transformed spontaneous firing rates); **adj. p < 0.01, NS adj. p > 0.05.