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Neurite length was increased in cultured neurons from AEP−/− mice. A, Examples of neurons cultured from AEP+/+ (top) and AEP−/− (bottom) mice. The identity of longest neurites of individual neurons is indicated by arrows. Scale bar: 100 μm. B, Mean (±SEM) length of the longest neurites in cultures of adult DRG neurons from AEP+/+, AEP+/−, and AEP−/− mice measured at 72 h in vitro.
