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. 2021 Jan 12:1–11. doi: 10.1080/07315724.2020.1856013

Table 2.

Univariate and Multivariate Cox Regression Analysis of 25(OH) D Levels, Serum Calcium Tertiles and In-Hospital Mortality in Severe COVID-19 Patients.

  Model 1
Model 2
Model 3
  HR 95% CI p HR 95% CI p HR 95% CI p
25 (OH) D >30 μg/l 1 1 1
20–29 μg/l 1.26 [0.32–5.04] 0.74 1.41[0.35–, 5.6] 0.62 1.3 [0.3–5.7] 0.73
10–19 μg/l 3.23 [1.06–9.8] 0.039 3.41 [1.11–10.4] 0.031 2.7 [0.8–9.4] 0.1
<10 μg/l 4.33 [1.43–13.1] 0.009 5.9 [1.77–19.5] 0.004 6.9 [2.0–24.1] 0.002
Serum CaT T1 [2.21–2.48] mmol/l 1 1 1
T2 [2.06–2.20]mmol/l 3.3 [1.12–9.6] 0.03 3.95 [1.34–11.7] 0.013 3.34 [1.03–10.8] 0.045
T3 [1.49–2.05] mmol/l 5.1 [1.9–13.5] 0.001 5.7 [2.12–15.0] 0.001 6.2 [2.1–18.3] 0.001

25(OH) D: 25-hydroxy vitamin D, Serum CaT: Serum calcium tertiles. Model 1: unadjusted model, Model 2: adjusted for age and sex, Model 3: adjusted for model 2, acute kidney injury, cardiac injury, blood glucose, CRP, NLR, LDH, albumin and total cholesterol. HR: Hazard ratio, 95% CI: 95 % confidence interval.

Bold values are statistically significant at p < 0.05.