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. 2021 Jan 19;16:63. doi: 10.1186/s13018-021-02201-2

Fig. 4.

Fig. 4

Regulatory networks. a The miRNA-gene network. b The miRNA-transcription factor (TF)-gene regulatory network. Circles, inverted triangles, and diamonds represent genes, miRNAs, and TFs, respectively. Red and blue represent upregulated and downregulated genes, respectively. T shapes, lines, and arrows represent miRNA-gene regulatory relationships, protein-protein interactions, and TF-gene regulatory relationships, respectively