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. 2021 Jan 19;19:11. doi: 10.1186/s12916-020-01883-5

Fig. 2.

Fig. 2

Colocalization analysis of genetic variants associated with TMEM106B expression in GTEx cerebellum and AD risk. Created using locuscomparer R package. Coloc PP0 = 0.031, PP1 = 0.002, PP2 = 0.735, PP3 = 0.037, and PP4 = 0.196. The eQTLs dataset is from GTEx cerebellum (n = 209). The AD GWAS dataset is from the IGAP including 21,982 AD and 41,944 cognitively normal controls