Table 2.
Various recombinant probiotics secreting IL-10
| Probiotics | Protein | Vector | Promoter | amount | References |
|---|---|---|---|---|---|
| L. lactis Thy12 | Human IL-10 | Chromosome integrated | PthyA (constitutive) | 13.7 ng/mL | [35] |
| L. lactis | Murine IL-10 | pLB263 | PgroESL (Inducible) | 40.72 ng/mL | [45] |
| L. lactis MG1363 | Murine IL-10 | pT1MIL10 | P1 (constitutive) | 630 ng/mL | [41] |
| B. longum NCC2705 | Human IL-10 | pLR | Phup (constitutive) | 22 pg/mL | [40] |
| B. breve UCC2003 | Human IL-10 | pESH100 | Pgap (constitutive) | 1.9 ng/mL | [47] |
| B. bifidum BS42 | Murine IL-10 | pBESTExp4:IL-10 | PdnaK (constitutive) | 7 ng/mL | [46] |
| B. bifidum BS42 | Murine Il-10 | pBESTSP1181:IL-10 | PdnaK (constitutive) | 24 ng/mL | [46] |
| B. bifidum BGN4 | Human IL-10 | pBESIL10 | Pgap (constitutive) | 1473 ng/mL | This study |