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. 2020 Oct 24;42(3):753–765. doi: 10.1002/hbm.25260

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© 2020 The Authors. Human Brain Mapping published by Wiley Periodicals LLC.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Correlations between brain structural and white matter (WM) microstructural changes and changes in THI scores and improvement of THI scores in tinnitus patients Pearson correlation showed a negative association between the GMV of the (a) right MFG/PreCG and ^ΔTHI scores (r = −.286, p = .024; uncorrected) and a negative association between the GMV of the (b) right MFG/PreCG and the % improvement of THI scores (r = −.362, p = .004; uncorrected). Pearson correlation showed a positive association between the AD value of the (c) right MCP and ^ΔTHI scores (r = .331, p = .009; uncorrected) and a positive association between the AD value of (d) the right MCP and the % improvement of THI scores (r = .280, p = .027; uncorrected). Pearson correlation showed a positive association between the AD value of the (e) left MCP and ^ΔTHI scores (r = .296, p = .017; uncorrected). AD, axial diffusivity; GMV, gray matter volume; MCP, middle cerebellar peduncle; MFG, middle frontal gyrus; PreCG, precentral gyrus; THI, Tinnitus Handicap Inventory