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. 2021 Jan;42(1):138–143. doi: 10.3174/ajnr.A6832

Table 1:

Diagnostic accuracy of imaging biomarkers on CTA in determining patients tested for SARS-CoV-2 (n = 106)

Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI)
Presence of GGO 75% (56–87) 81% (71–88) 58% (41–74) 90% (79–95)
Focal GGO 46% (29–64) 90% (81–95) 62% (39–81) 82% (72–89)
Bilateral GGO 57% (37–75) 82% (72–89) 53% (35–71) 84% (73–91)
Peripheral GGO 68% (49–82) 88% (79–94) 68% (48–83) 88% (79–94)
COVID-19-typical/in-determinatea 64% (46–79) 92% (84–94) 77% (50–92) 88% (74–95)

Note:—PPV indicates positive predictive value; NPV, negative predictive value.

a

COVID-19-typical alone gave a low sensitivity (36%) and was excluded from further analysis. COVID-19 CT imaging definitions are listed in On-line Table 1.