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. 2019 Jun 5;146(2):231–237. doi: 10.1002/ijgo.12860

Table 2.

Multivariate analysis of risk factors for sepsis, corrected for clustering using random effects (n=19 752)

Risk factors Sepsis Severe sepsis
aORa CI P valueb aORa CI P valueb
Hysterectomy 1.97 1.49–2.65 <0.001 1.97 0.83–2.46 0.033
Manual placenta removal 1.30 0.92–1.83 0.139 0.90 0.46–1.74 0.750
Intrauterine tamponade 1.77 1.21–2.59 0.004 2.60 1.47–4.59 0.002
Laparotomy 6.63 4.29–10.24 <0.001 5.35 2.61–10.98 <0.001
Brace sutures 1.09 0.66–1.81 0.7369 1.36 0.62–2.99 0.454
Artery ligation 1.48 0.94–2.34 0.098 2.50 1.28–4.89 0.010
Age, y 0.891 0.652
20–25 y 1 1
25–30 y 0.93 0.67–1.27 1.36 0.72–2.56
30–40 y 1.02 0.75–1.39 1.63 0.87–3.07
>40 0.76 0.30–1.91 1.37 0.32–5.79
≤20 1.09 0.69–1.73 1.40 0.56–3.46
Cesarean delivery 1.99 1.49–2.65 <0.001 1.43 0.83–2.46 0.197
Estimated blood loss, mL 0.006 0.139
≤1000 1 1
1001–2000 1.65 1.21–2.26 1.66 0.89–3.10
>2000 1.53 0.99–2.40 2.17 0.99–4.78
Systolic blood pressure, mm Hg <0.001 0.003
≥100 1 1
90–99 0.85 0.61–1.18 1.05 0.58–1.98
<90 1.57 1.17–2.13 2.36 1.32–4.19
Primary cause of hemorrhage 0.016 0.002
Atony 1 1
Trauma 1.40 1.05–1.88 0.93 0.52–1.66
Placenta previa/accreta 0.91 0.63–1.32 0.47 0.22–1.02
Other 1.54 1.06–2.23 2.37 1.31–4.29
Nonhospital delivery 1.34 0.96–1.88 0.088 1.12 0.62–2.03 0.713
Signs of hemodynamic instability 1.76 1.25–2.47 0.001 2.60 1.24–5.43 0.008

Abbreviations: aOR, adjusted odds ratio; CI, confidence interval.

a

Logistic regression adjusting for all variables in the table and random effects to correct for clustering by facility.

b

Based on likelihood ratio testing.