Fig. 6.

Suppression of tactile-elicited whisker afferent impulses by vincristine and vinblastine. A: sample traces show whisker afferent impulses evoked by a 38-µm whisker hair displacement in a whisker hair follicle before (control, top) and following the bath application of 100 µM vincristine for 30 min (bottom). B: summary data show whicker afferent impulse frequencies of the dynamic phase (left) and the static phase (right) in the control (open bars, n = 6) and following the bath application of 100 µM vincristine (closed bars, n = 6). C: summary data show whisker afferent impulse frequencies of the dynamic phase (left) and the static phase (right) in the control (open bars, n = 6) and following the bath application of 100 µM vinblastine (closed bars, n = 6). Data represent the means ± SE. NS, not significantly different; ***P < 0.001, paired Student’s t test.