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. 2021 Jan 15;13:45–58. doi: 10.2147/BCTT.S294166

Table 1.

Breast Magnetic Resonance (BMR) and Histology Correlation of Silicone-Induced Granuloma of Breast Implant Capsule (SIGBIC)

Breast Magnetic Resonance Histology
Extracellular silicone
  • Restricted to intracapsular space

  • Mass with hypersignal at T2 weighted sequences

  • Black-drop signal

  • Late contrast enhancement

  • Extracellular and intracellular silicone

  • Predominance of extracellular silicone

  • Germinal centers of lymphocytes

  • Diffuse infiltration by lymphocytes at the fibrous capsule

Intracellular silicone
  • Same findings from intracapsular

  • Pericapsular edema

  • Lymph node involvement

  • Early contrast enhancement of the extracapsular content

  • Intracapsular collection

  • Extracellular and intracellular silicone

  • Predominance of intracellular silicone

  • More severe infiltration by lymphocytes at the fibrous capsule

  • Collection with histiocytes and lymphocytes