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. 2021 Jan 19;16(1):e0245526. doi: 10.1371/journal.pone.0245526

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© 2021 Kimura et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — (A) Unsupervised consensus clustering classified 25 cases of ADRN-cluster neuroblastoma into two subgroups, ATRX- and MYCN-clusters, characterized by genetic alterations. Clinical data and mutational landscapes are also shown. The results of copy number analysis based on TCS data in (B) ATRX-cluster and (C) MYCN-cluster are shown. TCS, targeted capture sequencing. Broad and focal deletions/gains and amplifications in the coding region were also annotated.