Table 3. Multivariate analyses^* of risk factors associated with severe illness and death in patients with COVID-2019.

Risk factors	OR (95% CI)	P value
Severe illness vs Non-severe illness
Male	1.33 (1.05 to 1.67)	0.017
50–59 years of age (vs. 14–49 yrs)	1.29 (0.92 to 1.81)	0.144
60–69 years of age (vs. 14–49 yrs)	1.15 (0.84 to 1.56)	0.382
≥70 years of age (vs. 14–49 yrs)	2.30 (1.66 to 3.21)	<0.001
Peak temperature≥38.5°C	1.26 (0.99 to 1.59)	0.058
Experience Breath shortness	1.38 (1.09 to 1.73)	0.006
Experience dyspnea	2.09 (1.64 to 2.65)	<0.001
Experience anorexia	1.65 (1.31 to 1.08)	<0.001
Critical illness survivors vs Death§
Male	1.68 (1.11 to 2.56)	0.014
50–59 years of age (vs. 14–49 yrs)	6.79 (2.83 to 18.49)	<0.001
60–69 years of age (vs. 14–49 yrs)	11.02 (4.88 to 28.74)	<0.001
≥70 years of age (vs. 14–49 yrs)	17.99 (8.09 to 46.42)	<0.001
With respiratory disease	2.48 (1.16 to 5.56)	0.022
With carcinoma	4.11 (1.21 to 16.11)	0.029
No cough	2.46 (1.41 to 4.35)	0.002
Experience dyspnea	2.66 (1.77 to 4.04)	<0.001
Time of oxygen therapy initiation (days after onset of hypoxia symptoms) a
Day < = 2	Reference
Day >2	1.92 (1.20 to 3.10)	0.007

*Multivariable logistic regression analyses were performed. Age, hypertension, coronary, respiratory disease, carcinoma were not highly correlated with each other (Spearman’s rank correlation coefficients were calculated; r<0.3 for all), which indicated little evidence for taking account of collinearity in multivariate analyses.

^§ Only critical cases were included in the analysis.

^a Only critical illness patients who reported hypoxia symptoms and received supplementary oxygen treatment were included in the analysis.