Correction: Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans

After the publication of this article [1] the authors noticed citation errors in Table 2. The citations for item 5 listed under pyrethroids and items 2, 3, and 4 listed under temephos refer to the wrong references and these citations have been corrected in the updated Table 2 below. The citations for items 1, 3 and 4 listed under pyrethroids and item 1 listed under temephos are also incorrect and should cite references that have been omitted from the reference list. These citations have been corrected in the updated Table 2 below and the following corresponding references 79–82 should be added to the reference list:

• 79Bariami V, Jones CM, Poupardin R, Vontas J, Ranson H. Gene amplification, ABC transporters and cytochrome P450s: unraveling the molecular basis of pyrethroid resistance in the dengue vector, Aedes aegypti. PLoS Negl Trop Dis. 2012;6: e1692. pmid:22720108
• 80Saavedra-Rodriguez K, Suarez AF, Salas IF, Strode C, Ranson H, Hemingway J, et al. Transcription of detoxification genes after permethrin selection in the mosquito Aedes aegypti. Insect Mol Biol. 2012;21: 61–77. pmid:22032702
• 81David J-P, Faucon F, Chandor-Proust A, Poupardin R, Riaz MA, Bonin A, et al. Comparative analysis of response to selection with three insecticides in the dengue mosquito Aedes aegypti using mRNA sequencing. BMC Genomics. 2014;15: 174. pmid:24593293
• 82Strode C, de Melo-Santos M, Magalhaes T, Araujo A, Ayres C. Expression profile of genes during resistance reversal in a temephos selected strain of the dengue vector, Aedes aegypti. PloS One. 2012;7: e39439. pmid: 22870187

Updated Table

Table 2. The main genes identified by transcriptomic studies specifically targeting expression responses to insecticide selection or exposure.

Species	Source	Selection	RR	Genes detected as overexpressed	Ref.
		pyrethroids
Aedes aegypti	Cuba, Cayman	historical	30–1,000A	CYP9J9*, CYP9J10*, CYP9J26*, CYP9J27*, CYP9J28*, CYP6BB2*, 3 other P450 or related genes*, GSTE4*, ABCB4*, 2 UGT genes*	[79]
Ae. aegypti	Singapore	10 generations	1,650B	CYP9M4, CYP9M5, CYP9M6, CYP6Z7, CYP6Z8, CYP6BB2, CYP6F2, CYP6F3, 2 other P450 or related genes	[52]
Ae. aegypti	Mexico, Peru	5 generations	2.1–10.2A	CYP9J28*, CYP9J32*, CYP9J9*, 8 other P450 genes*, 2 CCE genes*, 2 GST genes*, aldo-keto reductase 4118*	[80]
Ae. aegypti	Bora Bora	10 generations	3.78C	aldo-keto reductase 4088	[81]
Ae. albopictus	Malaysia	exposure		CYP6P12, 16 other P450 genes, 2CCE genes, 5 GST genes, 1 UGT gene, 1 aldehyde oxidase gene, 11 cuticular protein genes, multiple other gene families	[55]
		temephos
Ae. aegypti	Brazil	20 generations	175D	CYP6N12, CCEAE3A, GSTX2, Aldehyde oxidase AO10382	[82]
Ae. aegypti	Thailand	exposure	5.9–9.85E	CCEAE3Α, CCEAE6Α, 1 other CCE gene, CYP6Z8, CYP9M9, CYP6AH1, CYP4H28	[59]
Ae. aegypti	Colombia	exposure	15 A,E	CYP6N12, CYP6M11, CYP6F3, 1 UGT gene	[19]
Ae. aegypti	Mexico, Peru	5 generations	42–390A	CYP4H28, CYP6F3, CYP6Z8, CYP9M9, 9 other P450 genes (8 CYP6 or CYP9), 8 GST genes, 10 CCE genes, AO10382, 7 other Redox genes	[57]
Ae. albopictus	Greece	12 generations	6.4F	CCEAE6A, CCEAE3A, 1 other CCE gene, CYP6M11, 7 other P450 genes, GSTX2, 1 other GST gene, 1 ABC gene, 5 UGT genes	[14]

Bold text denotes genes detected across studies; underlined text denotes genes detected across species.

The susceptible strain used to calculate the RR was New Orleans (A), SMK (B), Bora Bora (C), Rockefeller (D), Phatthalung (E) or a parental unselected line (F).

* genes significant in 2 or more comparisons.

Abbreviations: CCE, carboxy/cholinesterases; GST, glutathione S-transferases; P450, cytochrome P450 monooxygenases; RR, resistance ratio; Ref., Reference; UGT, UDP-glycosyltransferases.