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. 2021 Jan 19;16(1):e0245581. doi: 10.1371/journal.pone.0245581

Fig 3. The expression pattern and functional significance of BIRC7/Livin pre and post- FOLFOX treatment in human colorectal cancer (scale bar = 50 μm for H&E and scale bar = 100 μm for IHC).

Fig 3

A) A bar chart showing the age distribution of different CRC subtypes used in the study in Zaria Nigeria. B) Normal colorectal sections showing negative expression of BIRC7/Livin Scale bar, 20 um. C) Colorectal mucinous adenocarcinoma sections showing positive expression of BIRC7/Livin pre-FOLOFOX treatment, Scale bar, 20 um. D) Colorectal mucinous adenocarcinoma lesions showing increase expression of BIRC7/Livin post-FOLFOX treatment. E-G) Colorectal cancer not otherwise specified (well and moderate differentiated) sections pre and post-FOLFOX chemotherapy showing increase expressions of BIRC7/Livin Scale bar, 20 um. H-K) BIRC7/Livin expression pattern typified in dot plot and showing pattern of the proteins expression using quantitative analysis technique. L-M) Representative IF images showing positive expression of BIRC7 in mucinous CRC histology and CRC not otherwise specified.