Table 4. Creatinine values of colorectal cancer-bearing rats treated with aspirin with or without neo-adjuvant FOLFOX.
| Treatments | Creatinine values (umol/L) | p-valuea |
|---|---|---|
| Normal | 33.3±26.5 | 0.0001 |
| Cancer induced | 65.00±8.48 | |
| Cancer induced* | 65.00±8.48 | |
| Aspirin alone | 4.75± 1.50 | 0.001 |
| Cancer induced | 65.00±8.48 | |
| Aspirin plus FOLFOX (Sequentially) | 4.50±2.12 | 0.003 |
| Cancer induced | 65.00±8.48 | |
| Aspirin plus FOLFOX (Concurrently) | 3.40± .89 | 0.0001 |
| Cancer induced | 65.00±8.48 | |
| 5-FU alone | 11.00±5.65 | 0.007 |
Values are presented as mean±SD.
aThe result is significant when p <0.05.