Ingenuity Canonical Pathway analysis of signature genes identified from ipsilateral hemipshere after stroke. A-C, Significantly perturbed genes at acute (A, 1h and 1d)), sub-acute (B, 1w and 2w) and recovery (C, 2m) time points. Significant pathways are presented with blue and red bars indicating down and up-regulation, respectively. D, Expression profiles of pattern recognition receptors over time. Tlr8, Tlr9, Toll-like receptor; Clec9a, Clec4e, Clec5a, lectin-receptor families.