Table 3. Single and cumulative nephrotoxins frequency and incidence of acute kidney injury (AKI).
Number of drugs | Common drugs | Total usage | Incidence of AKI | P-value |
One drug use | Vancomycin | 126 (16.8%) | 24 (19%) | 0.07 |
Tazobactem/piperacillin | 97 (12.9%) | 09 (9.3%) | ||
Levetiracetam | 18 (2.4%) | 02 (11.1%) | ||
Colistimethate | 09 (1.2%) | 01 (11.1%) | ||
Two drug use | Vancomycin Colistimethate | 97 (12.9%) | 22 (22.6%) | 0.03 |
Vancomycin, Tazobactem/piperacillin | 25 (3.3%) | 5 (20%) | ||
Vancomycin Acyclovir | 4 (0.5%) | 1 (25%) | ||
Three or more drug use | Vancomycin, Colistimethate, Amphotericin | 22 (2.9%) | 4 (18.1%) | 0.09 |
Vancomycin, Levetiracetam, Phenytoin | 22 (2.9%) | 2 (9%) | ||
Vancomycin, Colistimethate, levetericetam | 13 (1.7%) | 4 (30.7%) |