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. 2020 Dec 20;12(12):e12183. doi: 10.7759/cureus.12183

Table 3. Single and cumulative nephrotoxins frequency and incidence of acute kidney injury (AKI).

Number of drugs Common drugs Total usage Incidence of AKI P-value
One drug use Vancomycin 126 (16.8%) 24 (19%) 0.07
Tazobactem/piperacillin 97 (12.9%) 09 (9.3%)
Levetiracetam 18 (2.4%) 02 (11.1%)
Colistimethate 09 (1.2%) 01 (11.1%)
Two drug use Vancomycin Colistimethate 97 (12.9%) 22 (22.6%) 0.03
Vancomycin, Tazobactem/piperacillin 25 (3.3%) 5 (20%)
Vancomycin Acyclovir 4 (0.5%) 1 (25%)
Three or more drug use Vancomycin, Colistimethate, Amphotericin 22 (2.9%) 4 (18.1%) 0.09
Vancomycin, Levetiracetam, Phenytoin 22 (2.9%) 2 (9%)
Vancomycin, Colistimethate, levetericetam 13 (1.7%) 4 (30.7%)