Fig. 1.

Editing of ODF2 and silencing of IFT88 reduces the number and length of primary cilia. a, d Relative expression of target mRNA. In a, n = 3. In d, n = 5. Bars indicate minimum and maximum RQ. b, e Percent of cells possessing primary cilia. In b, control n = 6, ODF2e n = 4. In e, control n = 7, IFT88si n = 6. Bars indicate ± SEM. c, f Length of primary cilia. In c, control n = 493, ODF2e n = 483. In f, control n = 371, IFT88si n = 400 cells counted. Bars indicate minimum and maximum ciliary lengths measured; center line is median length