Table 2 Patient characteristics reported by Meis et al. (2003, MFMU) vs. Blackwell et al. (2019, PROLONG).
| MFMU | PROLONG | |||
|---|---|---|---|---|
| 17-OHPC (n = 310) | Placebo (n = 153) | 17-OHPC (n = 1130) | Placebo (n = 578) | |
| MFMU: Maternal-Fetal Medicine Units; PROLONG: Progestinʼs Role in Optimizing Neonatal Gestational Length; 17-OHPC: 17-hydroxyprogesterone caproate; BMI: body mass index. a Described as “non-Hispanic black”, b Described as “non-Hispanic white”. Data are presented as mean ± standard deviation or as a percentage (%). | ||||
| Age (years) | 26.0 ± 5.6 | 26.5 ± 5.4 | 30.0 ± 5.2 | 29.9 ± 5.2 |
| BMI prior to pregnancy | 26.9 ± 7.9 | 26.0 ± 7.0 | 23 (21 – 27) | 23 (21 – 27) |
| > 1 previous preterm birth (%) | 27.7 | 41.2 | 13.1 | 12.1 |
| Gestational age when the previous preterm birth occurred (weeks) | 30.6 ± 4.6 | 31.3 ± 4.2 | 32 (28 – 35) | 33 (29 – 35) |
| Ethnicity (%) | ||||
|
59.0 a | 58.8 a | 6.5 | 7.1 |
|
25.5 b | 22.2 b | 88.8 | 87.2 |
|
0.6 | 0.7 | 2.0 | 3.8 |
|
13.9 | 17.0 | – | – |
|
1.0 | 1.3 | 2.7 | 1.9 |
| Marital status (%) | ||||
|
51.3 | 46.4 | 89.6 | 90.3 |
|
38.4 | 41.8 | 7.6 | 6.9 |
|
10.3 | 11.8 | 2.7 | 2.8 |
| Smoking during pregnancy (%) | 22.6 | 19.6 | 8.1 | 7.1 |
| Alcohol during pregnancy (%) | 8.7 | 6.5 | 2.1 | 3.1 |