Figure 4.

The effect of CaSR- stimulated PMN function can be inhibited by GW4869. (a) The results of green fluorescence in cardiomyocytes cocultured with PMNs and PMN-derived exosomes. (b) The apoptosis rate of cardiomyocytes. Q1: necrotic cells. Q2: late apoptotic cells. Q3: living cells. Q4: early apoptotic cells. Data are shown as the means ± SD; ^#P < 0.05 vs. the control group, ^∗P < 0.05 vs. the H/R group, and ^△P < 0.05 vs. the CIN group. Data are representative of three independent experiments.