Table 3.

Clinical variables with high predictive accuracy for freezing of gait using univariate logistic regression analysis.

OR estimates
Effect	Point estimate	95% confidence limits		R 2	p value
PIGD phenotype	10.79	4.48	26.00	0.18	<0.0001
MDS-UPDRS Bal-Gait score1	1.33	1.20	1.49	0.15	<0.0001
LED2	1.24	1.14	1.36	0.14	<0.0001
MDS-UPDRS motor complications score	1.30	1.16	1.47	0.11	<0.0001
Disease duration	1.18	1.11	1.26	0.14	<0.0001
Cognitive impairment3	3.00	1.51	5.97	0.05	0.001
Psychosis	4.07	1.55	10.64	0.04	0.003
Urinary problems	3.27	1.68	6.37	0.06	0.0003

ORs indicate the increase in odds for FOG resulting from a one-unit change in effect parameters: 1 rating point for an MDS-UPDRS rating scale score, or from 0 to 1 (effect absent to effect present), e.g., for cognitive impairment. For example, for a one-unit increase in the MDS-UPDRS Bal-Gait score, there is a 33% increase in the odds of developing freezing. ¹The Balance-Gait score: the MDS-UPDRS PIGD score minus the freezing score. ²Levodopa equivalent dose (100 mg units). ³MCI or dementia.