Fig. 1.

(A) Lactulose/mannitol urine concentrations ratio serving as a measure of intestinal permeability. The red line indicates the cut off. (B) Faecal calprotectin serving as a measure of intestinal inflammation. The red line indicates the level of 100 ​μg/g clinically used as a marker of intestinal inflammation in inflammatory bowel disease. Boxes represent values between quartiles 1 and 3, and a thick line indicates the median. Whiskers show the max and min values located above the top or below the bottom of the box, respectively, within a 1.5 interquartile distance. Circles denote outliers values located outside a 1.5 interquartile distance, and stars denote outliers located outside a 3 interquartile distance. Two extreme primary Sjögren’s syndrome outliers at 1113 and 2037 ​μg/g are not shown, but are included in the calculation of the box and whiskers. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)