Table 1.
Subcellular localization categories statistics of identified proteins and differentially expressed proteins. All proteins identified by mass spectrometer were classified six categories according to UniprotKB Subcellular localization database. If a protein was matched to more than one category, its predominant subcellular location was used for functional grouping.
| Subcellular localization | Number of proteins |
Percent |
Fisher's exact test P value | ||
|---|---|---|---|---|---|
| Identified | Different | Identified | Different | ||
| ECM | 52 | 6 | 1.59% | 1.34% | 7.37E-01 |
| Secreted | 146 | 34 | 4.47% | 7.59% | 9.26E-04 |
| Cytoskeleton | 157 | 20 | 4.80% | 4.46% | 6.77E-01 |
| Nucleus | 350 | 36 | 10.71% | 8.04% | 9.83E-01 |
| Cytosol | 51 | 10 | 1.56% | 2.23% | 1.51E-01 |
| Membrane | 835 | 150 | 25.54% | 33.48% | 3.20E-05 |