Table 2.
Proportion of BPD and ADHD in individuals with the other diagnosis, and in individuals whose relatives have the other diagnosis
No. of individuals |
Proportion of BPD—outcome Percent (95% CI) |
Proportion of ADHD—outcome Percent (95% CI) |
|||
No ADHD | ADHD | No BPD | BPD | ||
Within individual | |||||
Both sexesa | 2,113,902 | 0.3% (0.3–0.3) | 3.6% (3.4–3.7) | 3.8% (3.8–3.8) | 30.9% (30.0–31.9) |
Females onlya | 1,031,987 | 0.6% (0.6–0.6) | 8.0% (7.7–8.3) | 2.7% (2.7–2.8) | 29.6% (28.6–30.5) |
Males onlya | 1,081,915 | 0.1% (0.1–0.1) | 1.0% (0.9–1.0) | 4.8% (4.7–4.8) | 40.1% (37.4–42.8) |
Full siblings | No. of pairsb | ||||
Both sexes | 2,211,396 | 0.4% (0.4–0.4) | 0.9% (0.9–1.0) | 3.4% (3.4–3.4) | 7.8% (7.2–8.4) |
Female outcome female exposure | 523,464 | 0.7% (0.7–0.7) | 1.9% (1.6–2.1) | 2.6% (2.5–2.6) | 6.6% (5.8–7.4) |
Female outcome male exposure | 552,516 | 0.7% (0.7–0.8) | 1.5% (1.3–1.7) | 2.6% (2.6–2.7) | 8.6% (6.2–11.0) |
Male outcome female exposure | 552,516 | 0.1% (0.1–0.1) | 0.3% (0.2–0.4) | 4.2% (4.2–4.3) | 8.4% (7.6–9.3) |
Male outcome male exposure | 582,900 | 0.1% (0.1–0.1) | 0.2% (0.2–0.3) | 4.1% (4.0–4.2) | 10.6% (7.9–13.3) |
Half-siblings | Pairsb | ||||
Both maternal and paternal | 663,566 | 0.9% (0.8–0.9) | 1.3% (1.2–1.3) | 7.7% (7.6–7.8) | 10.6% (9.9–11.4) |
Notes: 95% CI 95% confidence intervals
aCluster-robust standard errors based on mothers as clusters
bNumber of unique ways of combining pairs, i.e., a pair may be included twice, first with A as outcome person and B as exposure person, then with B as outcome person and A as exposure person