Table 2.
Means and standard deviations of all variables included in the statistical analyses (N = 327)
| M | SD | |
|---|---|---|
| Depressive symptoms T1 | 1.62 | 0.49 |
| Depressive symptoms T2 | 1.49 | 0.49 |
| Depressive symptoms T3 | 1.52 | 0.53 |
| Depressive symptoms T4 | 1.55 | 0.54 |
| Depressive symptoms T5 | 1.53 | 0.53 |
| Depressive symptoms T6 | 1.59 | 0.56 |
| Adolescent-reported parental criticism T1 | 1.64 | 0.47 |
| Adolescent-reported parental criticism T2 | 1.67 | 0.51 |
| Adolescent-reported parental criticism T3 | 1.76 | 0.57 |
| Adolescent-reported parental criticism T4 | 1.80 | 0.56 |
| Adolescent-reported parental criticism T5 | 1.77 | 0.57 |
| Adolescent-reported parental criticism T6 | 1.77 | 0.57 |
| Mother-reported parental criticism T1 | 1.57 | 0.39 |
| Mother-reported parental criticism T2 | 1.54 | 0.38 |
| Mother-reported parental criticism T3 | 1.52 | 0.38 |
| Mother-reported parental criticism T4 | 1.54 | 0.38 |
| Mother-reported parental criticism T5 | 1.54 | 0.39 |
| Mother-reported parental criticism T6 | 1.52 | 0.38 |
| Parental criticisma | 1.63 | 0.32 |
| PRS MDD 5 × 10−8b | −8.75 × 10−6 | 2.87 × 10−3 |
| PRS MDD 5 × 10−7 | −3.92 × 10−5 | 2.38 × 10−3 |
| PRS MDD 5 × 10−6 | −1.56 × 10−5 | 1.35 × 10−3 |
| PRS MDD 5 × 10−5 | −1.67 × 10−5 | 7.15 × 10−4 |
| PRS MDD 5 × 10−4 | −4.88 × 10−6 | 2.88 × 10−4 |
| PRS MDD 5 × 10−3 | −7.41 × 10−8 | 1.14 × 10−4 |
| PRS MDD 0.01 | 6.84 × 10−7 | 8.78 × 10−5 |
| PRS MDD 0.05 | 1.28 × 10−6 | 4.41 × 10−5 |
| PRS MDD 0.10 | 1.12 × 10−6 | 3.16 × 10−5 |
| PRS MDD 0.20 | 9.45 × 10−7 | 2.20 × 10−5 |
| PRS MDD 0.30 | 7.19 × 10−7 | 1.75 × 10−5 |
| PRS MDD 0.40 | 6.32 × 10−7 | 1.48 × 10−5 |
| PRS MDD 0.50 | 5.52 × 10−7 | 1.28 × 10−5 |
PRS MDD […] = polygenic risk score for major depression, calculated based on the mentioned p-value threshold
aAdolescent- and mother-reports of parental criticism across six successive years were combined into a single multi-informant longitudinal average, with higher levels representing higher levels of parental criticism. For the analyses, this score was standardized to facilitate estimation and interpretation
bThe PRS MDD 5 × 10−8 score was based on the meta-analysis by Hyde et al. (2016) and corrected for adolescent age, sex, and population stratification. The other 12 PRS MDD scores with different p-value thresholds were based on the 23andMe summary statistics and also corrected for adolescent age, sex, and population stratification. For the analyses, all PRS MDD were standardized to facilitate estimation and interpretation