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. 2020 Aug 12;268(1):265–275. doi: 10.1007/s00415-020-10054-8

Table 2.

Summary of data relating length of hospital stay, engraftment time and complications of autologous haematopoietic stem cell transplantation (auto-HSCT) in the four patients treated for refractory stiff person syndrome

Patient Age/Gender Complications during priming and harvesting Engraftment time after auto-HSCT (neutrophils > 0.5 × 109/L and platelets > 20 × 109/L) Length of hospital stay for auto-HSCT Required blood products/ transfusions Complications during auto-HSCT Long term sequelae
A 36/F

Headache

E.coli UTI

Pain

Neutrophils:

13 days

Platelets:

12 days

26 days Yes

Enterococcus UTI

Pulmonary embolism

Mucositis and rectal bleeding

Post-menopausal symptoms

Alive with no complications
B 48/F None

Neutrophils:

11 days

Platelets:

never dropped below 50

18 days No

ESBL UTI

Transient exacerbation of diabetes due to steroids

Alive with no complications
C 37/F Gram-negative pantoea agglomerans from Hickman line-treated successfully with antibiotics

Neutrophils:

14 days

Platelets:

13 days

21 days Yes

Febrile neutropenia covered with antibiotics

Transiently deranged LFTs

Transient CMV and EBV viraemia

Alive with no complications
D 52/M None

Neutrophils:

11 days

Platelets:

10 days

16 days Yes

Coagulase-negative staphylococcus line infection

Transient EBV viraemia

URTI (RSV)

Alive with no complications