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Prevalence and severity of ATTRv polyneuropathy (PN) in the different genotypes
| Mutation | Number of subjects with PN | NIS-LL (mean) in subjects with PN |
|---|---|---|
| Phe64Leu | 8/22 (36%) | 32.4 |
| Val30Met | 10/13 (77%) | 41.2 |
| Glu89Gln | 7/11 (64%) | 20.1 |
| Ile68Leu | 2/5 (40%) | 6.5 |
| Thr49Ala | 4/4 (100%) | 25.0 |
| Others | 3/7 (43%) | 19.6 |
| Total | 34 (55%) | 28.9 |
NIS-LL Neuropathy Impairment Score at Lower Limbs, PN polyneuropathy
