Table 3.
Adherence and persistence indicators
| Parameter | Overall cohort | Complete switch cohort | ||
|---|---|---|---|---|
| LAI (n = 1,132) | Oral (n = 1,518) | LAI (n = 533) | Oral (n = 230) | |
| PDC | ||||
| Mean (SD) | 0.6 (0.3) | 0.3 (0.3) | 0.6 (0.3) | 0.4 (0.3) |
| Median (IQR) | 0.6 (0.2–0.9) | 0.1 (0.0-0.5) | 0.6 (0.2–0.9) | 0.4 (0.1–0.8) |
| Adherence, n (%) | ||||
| PDC ≥ 0.8 | 401 (35.4) | 176 (11.6) | 176 (33.0) | 50 (21.7) |
| Persistence, n (%) | ||||
| No 30-day gap | 299 (26.4) | 145 (9.6) | 138 (25.9) | 43 (18.7) |
| No 60-day gap | 461 (40.7) | 300 (19.8) | 203 (38.1) | 76 (33.0) |
| No 90-day gap | 546 (48.2) | 430 (28.3) | 245 (46.0) | 98 (42.6) |
IQR interquartile range, LAI long acting injectable antipsychotic, PDC proportion of days covered, SD standard deviation