Fig. 3.

Relation of auditory naming fMRI activation to age at onset of epilepsy across LTLE and RTLE patients. Activations are shown superimposed on coronal and sagittal images at p < 0.001, uncorrected and the crosshair indicates the orthogonal slices. A later age of onset (top row) was associated with stronger activations in the left anterior superior and middle gyrus (crosshair) and left inferior frontal gyrus, whereas an earlier age of onset (lower row) was related to weaker deactivation of the left supramarginal gyrus. Scatterplots show correlations of fMRI parameter estimate with age at onset of epilepsy (left TLE: red; right TLE: green). A anterior, L left, P posterior, R right, TLE temporal lobe epilepsy