Table 2.

Classification abilities of the ERT per subgroup

	AUC	95% CI	p value	Optimal cut-off	Sensitivity (%)	Specificity (%)
bvFTD vs. AD
Total score	0.52	0.34–0.63	0.830	–	–	–
Anger	0.55	0.40–0.67	0.532	–	–	–
Disgust	0.57	0.29–0.57	0.320	–	–	–
Fear	0.58	0.27–0.56	0.245	–	–	–
Happiness	0.63	0.49–0.77	0.086	–	–	–
Sadness	0.59	0.26–0.55	0.197	–	–	–
Surprise	0.51	0.34–0.63	0.856	–	–	–
bvFTD vs. presymptomatic carriers
Total score	0.83	0.72–0.95	< 0.001	50.5	89.4	78.1
Anger	0.89	0.82–0.96	< 0.001	12.5	74.5	90.6
Disgust	0.81	0.71–0.91	< 0.001	9.5	85.1	68.8
Fear	0.54	0.32–0.60	0.566	–	–	–
Happiness	0.87	0.79–0.96	< 0.001	14.5	78.7	84.4
Sadness	0.59	0.45–0.73	0.176	–	–	–
Surprise	0.62	0.48–0.75	0.069	–	–	–
bvFTD vs. controls
Total score	0.81	0.69–0.92	< 0.001	43.5	95.9	62.5
Anger	0.88	0.81–0.95	< 0.001	12.5	73.5	90.6
Disgust	0.72	0.61–0.84	< 0.001	7.5	77.6	59.4
Fear	0.54	0.41–0.68	0.517	–	–	–
Happiness	0.88	0.80–0.97	< 0.001	14.5	85.7	84.4
Sadness	0.57	0.43–0.72	0.277	–	–	–
Surprise	0.57	0.43–0.71	0.273	–	–	–
Presymptomatic carriers vs. controls
Total score	0.59	0.48–0.71	0.111	–	–	–
Anger	0.52	0.40–0.63	0.764	–	–	–
Disgust	0.62	0.50–0.73	0.045	11.5	63.3	66.0
Fear	0.51	0.39–0.62	0.918	–	–	–
Happiness	0.50	0.39–0.62	0.947	–	–	–
Sadness	0.56	0.44–0.68	0.317	–	–	–
Surprise	0.58	0.47–0.70	0.174	–	–	–
AD vs. controls
Total score	0.90	0.82–0.98	< 0.001	48.5	83.7	90.6
Anger	0.84	0.75–0.93	< 0.001	12.5	73.5	81.2
Disgust	0.82	0.73–0.91	< 0.001	9.5	61.2	90.6
Fear	0.57	0.45–0.70	0.284	–	–	–
Happiness	0.87	0.78–0.95	< 0.001	14.5	85.7	84.4
Sadness	0.73	0.61–0.84	0.001	4.5	65.3	71.9
Surprise	0.59	0.46–0.73	0.153	–	–	–

ERT Emotion Recognition Task, AUC area under the curve, CI confidence interval, bvFTD behavioural variant frontotemporal dementia, AD Alzheimer’s Dementia