Table 1.
MCI (n = 40) | Controls (n = 37) | p-value | |
---|---|---|---|
Age, mean ± SD, years | 72.8 ± 8.6 | 69.0 ± 10.4 | 0.15 |
Sex (M/F), (n/n) | 25/15 | 17/20 | 0.17 |
DM (n) | 3 | 6 | 0.30 |
HTN (n) | 9 | 14 | 0.21 |
OD/OS (n/n) | 20/20 | 19/18 | > 0.999 |
SE, mean ± SD, Diopter | −0.48 ± 2.1 | −0.45 ± 1.8 | 0.84 |
VA, mean ± SD, logMAR | 0.03 ± 0.05 | 0.04 ± 1.8 | 0.28 |
Retinal neuronal layer thickness, mean ± SD, μm | |||
Total retina | 315.1 ± 14.2 | 314.9 ± 14.4 | 0.87 |
RNFL | 20.0 ± 2.4 | 19.9 ± 2.5 | 0.95 |
GCL | 39.1 ± 3.8 | 38.3 ± 6.3 | 0.92 |
IPL | 34.6 ± 2.1 | 33.9 ± 3.6 | 0.47 |
INL | 37.2 ± 3.9 | 36.1 ± 3.3 | 0.20 |
OPL | 33.7 ± 4.7 | 33.5 ± 5.1 | 0.83 |
ONL | 67.5 ± 9.9 | 68.3 ± 8.5 | 0.96 |
RPE | 15.3 ± 1.7 | 16.0 ± 1.9 | 0.25 |
MCI = mild cognitive impairment, M = male, F = female, DM = diabetes mellitus, HTN = hypertension, SE = spherical equivalent, OD = right eye, OS = left eye, VA = visual acuity, logMAR = logarithm of the minimum angle of resolution, RNFL = retinal nerve fiber layer, GCL = ganglion cell layer, IPL = inner plexiform layer, INL = inner nuclear layer, OPL = outer plexiform layer, ONL = outer nuclear layer, RPE = retinal pigment epithelium, SD = standard deviation.
*p < 0.05.