Table 5.
Optical coherence tomography and optical coherence tomography angiography parameters of APOE-ε4 carriers and non-carriers.
| APOE-ε4 + | APOE-ε4- | p-value | |
|---|---|---|---|
| n | 10 | 18 | |
| Age, mean ± SD, years | 71.1 ± 7.1 | 73.2 ± 6.5 | 0.27 |
| Sex (M/F), (n/n) | 5/5 | 13/5 | 0.41 |
| Retinal microvasculature, mean ± SD | |||
| FAZ area (mm2)-SCP | 0.32 ± 0.09 | 0.31 ± 0.10 | 0.65 |
| FAZ area (mm2)-DCP | 1.04 ± 0.24 | 0.91 ± 0.26 | 0.21 |
| VD (%)—SCP | 14.4 ± 3.8 | 14.4 ± 3.5 | 0.83 |
| VD (%)—DCP | 24.3 ± 1.8 | 26.0 ± 2.0 | 0.03* |
| Retinal layer thickness, mean ± SD, μm | |||
| Total retina | 315.8 ± 14.2 | 316.2 ± 13.8 | 0.80 |
| RNFL | 21.0 ± 3.3 | 19.8 ± 1.8 | 0.45 |
| GCL | 39.7 ± 4.7 | 39.7 ± 3.3 | 0.60 |
| IPL | 35.6 ± 1.7 | 34.6 ± 1.9 | 0.15 |
| INL | 37.9 ± 3.5 | 36.6 ± 4.2 | 0.36 |
| OPL | 35.2 ± 4.9 | 32.2 ± 3.1 | 0.17 |
| ONL | 64.7 ± 9.1 | 69.3 ± 9.5 | 0.23 |
| RPE | 14.7 ± 1.7 | 15.7 ± 1.4 | 0.07 |
APOE = apolipoprotein E, M = male, F = female, FAZ = foveal avascular zone, SCP = superficial capillary plexus, DCP = deep capillary plexus, VD = vessel density, RNFL = retinal nerve fiber layer, GCL = ganglion cell layer, IPL = inner plexiform layer, INL = inner nuclear layer, OPL = outer plexiform layer, ONL = outer nuclear layer, RPE = retinal pigment epithelium, SD = standard deviation.
*p < 0.05.