Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structures of trypanosomatid FPPS. (A) Superimposed structures of T. cruzi (green; PDB ID: 4DWG), T. brucei (light purple; PDB ID: 4RXD), L. major (yellow; PDB ID: 4JZX) and human FPPS (white; PDB ID: 4H5E). Conserved residues of the active site are displayed in the inset. (B) Aromatic residues of the allylic substrate site hydrophobic pocket.
