Figure 1.

ECMs Are the Minimal Building Blocks of All Net Conversions by Metabolic Networks

For a Figure360 author presentation of this figure, see https://doi.org/10.1016/j.patter.2020.100177.

(A) The Elementary conversion modes for a small network are shown in blue, green, and red. Note that the red ECM can be written as a positive combination of the blue and green ECM, but that this cancels the production of B.

(B) The cone of steady-state conversions is shown in gray and is spanned by the blue and green ECM. The red ECM lies in the interior of the cone on the intersection with the $\dot{B}=0$ plane.