Table 2.
Unadjusted odds ratios (OR) and 95% confidence intervals (95% CI) between HSV-2 Serostatus and Select Risk Factors
| Positive vs. Negative |
Indeterminate vs. Negative |
|||||||
|---|---|---|---|---|---|---|---|---|
| Manufacturer’s Cutpoints |
Modified Cutpoints |
Manufacturer’s Cutpoints |
Modified Cutpoints |
|||||
| OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
| Age (per 1-year increase) | 1.06 | (1.03, 1.10) | 1.14 | (1.09, 1.18) | 1.07 | (0.98, 1.17) | 1.04 | (0.99, 1.09) |
| Household Size (per 1-person increase) | 1.42 | (1.18, 1.70) | 1.46 | (1.23, 1.72) | 1.26 | (0.97, 1.63) | 1.36 | (1.08, 1.70) |
| Education (Ref: <2 years) | ||||||||
| 2–4 Years | 0.17 | (0.04, 0.73) | 0.15 | (0.03, 0.69) | 0.19 | (0.03, 1.21) | 0.15 | (0.04, 0.57) |
| >5 Years | 0.14 | (0.03, 0.66) | 0.08 | (0.02, 0.44) | 0.15 | (0.02, 1.09) | 0.17 | (0.04, 0.68) |
| Household Income (Ref: <10,000) | ||||||||
| 10,000–29,999 | 0.79 | (0.41, 1.53) | 0.74 | (0.31, 1.81) | 1.53 | (0.33, 7.14) | 0.91 | (0.52, 1.59) |
| >30,000 | 0.95 | (0.33, 2.78) | 0.82 | (0.30, 2.25) | 0.82 | (0.10, 7.06) | 0.91 | (0.36, 2.30) |
| Married | 0.73 | (0.35, 1.53) | 1.70 | (0.30, 9.65) | 0.40 | (0.08, 1.95) | 0.53 | (0.28, 0.99) |
| Concurrent Partner | 0.61 | (0.18, 2.00) | 1.32 | (0.33, 5.32) | --- | --- | 0.31 | (0.08, 1.16) |
| Partner in Concurrent Relationship (Ref: No) | ||||||||
| Don’t Know | 1.09 | (0.62, 1.90) | 1.91 | (1.08, 3.38) | 1.64 | (0.23, 11.85) | 1.19 | (0.66, 2.17) |
| Yes | 1.94 | (0.93, 4.06) | 4.88 | (2.54, 9.37) | 4.29 | (0.74, 24.98) | 1.36 | (0.62, 2.95) |
| Frequency of Sex (Ref: < Once Per Week) | ||||||||
| > Once Per Week | 0.48 | (0.21, 1.08) | 0.50 | (0.17, 1.45) | 0.75 | (0.16, 3.57) | 0.51 | (0.22, 1.17) |
| No. of Sexual Partners (Ref: One) | ||||||||
| Two | 1.12 | (0.67, 1.90) | 2.08 | (1.00, 4.32) | 0.42 | (0.12, 1.47) | 0.78 | (0.44, 1.40) |
| Three or More | 1.41 | (0.84, 2.37) | 2.05 | (0.94, 4.47) | 1.20 | (0.39, 3.68) | 0.94 | (0.52, 1.70) |
| No. of Marriages (Ref: 0–1) | ||||||||
| >2 | 2.03 | (1.14, 3.61) | 3.66 | (1.84, 7.27) | 0.31 | (0.05, 2.08) | 1.41 | (0.63, 3.18) |
| Bacterial Vaginosis | 1.88 | (0.89, 3.97) | 3.17 | (1.35, 7.47) | 1.28 | (0.25, 6.49) | 1.79 | (0.91, 3.50) |
| Pregnancies (per 1-pregnancy increase) | 1.26 | (1.10, 1.43) | 1.38 | (1.21, 1.58) | 1.19 | (0.95, 1.50) | 1.15 | (1.00, 1.33) |
OR = odds ratio; CI = confidence interval