Table 3.

Results of univariate and multivariate analyses of prognostic factors for first-line PFS and OS in all eligible patients with unresectable pancreatic cancer.

Parameter	PFS			OS
	Univariate Analysis	Multivariate Analysis		Univariate Analysis	Multivariate Analysis
	p-value	RR (95% CI)	p-value	p-value	RR (95% CI)	p-value
Age ≥ 65 years	0.44			0.10
Gender(male)	0.11	1.82(1.09–3.02)	0.02	0.04	1.79 (1.03–2.83)	0.04
ECOG PS ≥ 2	0.28			0.55
Pancreatic tumor location	0.54			0.40
Liver metastasis	0.01			0.06
Number of metastatic sites ≥ 2	0.15			0.13
diabetes CA19-9(>629.5 ng/mL)	0.21 0.80			0.96 0.05
Stage IV	<0.01	2.61(1.05–6.49)	0.04	0.20
Second-line chemotherapy	0.86			0.07

Abbreviations: PFS progression-free survival, OS overall survival, RR relative risk, CI confidence interval, ECOG PS Eastern Cooperative Oncology Group performance status.