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. 2021 Jan 6;21(3):184. doi: 10.3892/ol.2021.12445

Table VII.

Influence of clinicopathological parameters on the prognosis of patients with esophageal squamous cell carcinoma.

OS PFS


Clinicopathological parameters Mean survival (months) Median survival (months) Log rank (Mantel-Cox) P-value Mean survival (months) Median survival (months) Log rank (Mantel-Cox) P-value
Age, years   0.087   0.768 0.122 0.726
  ≤60 27.682 24 21.197 16
  >60 27.615 22 20.364 12
Sex   1.495   0.222 0.627 0.429
  Male 26.485 24 20.224 13
  Female 29.780 30 22.422 12
Ethnicity   0.033   0.857 0.178 0.673
  Han 26.454 24 20.811 13
  Kazakh 28.189 24 20.187 12
Tumor location   1.429   0.489 1.127 0.569
  Upper 19.515   2 19.000   2
  Middle 27.575 24 21.739 12
  Lower 27.030 24 19.001 15
Tumor size   0.575   0.448 0.522 0.47
  <3 cm 28.223 32 22.102 20
  ≥3 cm 26.943 20 20.169 12
Differentiation   4.314   0.116 1.678 0.432
  Low 23.756 18 19.082 16
  Medium 25.890 24 19.992 13
  High 34.360 24 24.594 11
Depth of invasion   2.054   0.358 2.484 0.289
  Mucosal 37.833 48 34.000 48
  Muscle 28.697 24 20.375 12
  Full 25.635 22 20.182 12
TNM stage   9.200   0.027 10.006 0.019
  I 35.266 36 23.899 10
  II 29.520 28 23.049 18
  III 20.894 18 14.932 12
  IV 19.756 13 12.427   9
Lymph node metastasis   6.270   0.012 6.698 0.010
  No 30.248 31 23.134 18
  Yes 22.128 15 15.776 12
Vascular invasion   1.670   0.196 0.349 0.555
  No 28.826 24 21.083 12
  Yes 22.719 22 18.200 12
Nerve invasion 10.255   0.001 3.990 0.046
  No 30.223 24 22.089 14
  Yes 18.567 10 16.090 10
Radiotherapy or chemotherapy 10.202 <0.001 3.185 0.074
  No 23.157 18 24.228 12
  Yes 35.152 28 18.907 18

OS, overall survival; PFS, progression-free survival.