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. 2021 Jan 19;21:58. doi: 10.1186/s12935-021-01766-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — The expression of IRF4 was suppressed by miR-320c, miR-30a-5p and miR-27a-3p. Tregs were transfected with miR-320c mimic, mimic NC, miR-320c inhibitor or inhibitor NC. a QRT-PCR was performed to detect the expression of miR-320c and IRF4 in the modified Tregs. b WB was performed to explore the expression of IRF4 in the modified Tregs. Tregs were transfected with miR-30a-5p mimic, mimic NC, miR-30a-5p inhibitor or inhibitor NC. c QRT-PCR was performed to detect the expression of miR-30a-5p and IRF4 in the modified Tregs. d WB was performed to explore the expression of IRF4 in the modified Tregs. Tregs were transfected with miR-27a-3p mimic, mimic NC, miR-27a-3p inhibitor or inhibitor NC. e QRT-PCR was performed to detect the expression of miR-27a-3p and IRF4 in the modified Tregs. f WB was performed to explore the expression of IRF4 in the modified Tregs. (**P < 0.01, versus mimic NC; ^##P < 0.01, versus inhibitor NC)