Table 3.
Strategies | SNPs | Related Genes |
---|---|---|
The expression levels of mRNAs associated with SNPs using eQTL analysis(P < E-05) |
107 SNPs (see Additional file 1: Table S4) |
- |
The 5 SNPs with smallest p values | rs7203246 | EEF2K |
rs62292160 | ADRA2C | |
rs17170200 | TPK1 | |
rs2189164 | TACR3 | |
rs3786247 | LIPG | |
Related genes were involved in the modulation of immune functions or playing a role TB | rs1667908 | MBP |
rs7203246 | EEF2K | |
rs12712986 | TTC7A | |
Related genes interact in a regulatory network | rs4654400 | PTPRU |
rs7203246 | EEF2K | |
rs62292160 | ADRA2C | |
rs2189164 | TACR3 | |
rs3786247 | LIPG | |
rs1667908 | MBP | |
rs17170200 | TPK1 |
The table showed the strategy for screening the SNPs. First, 107 SNPs whose P value < E−05 were selected. In these 107 SNPs, the most differentially expressing 5 SNPs were selected, whose p value was less than E−07. 3 SNPs which played key roles in immune regulation or TB and 7 SNPs involved in the interaction network were select