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. 2021 Jan 20;22:23. doi: 10.1186/s12931-020-01612-9

Table 3.

Selected SNPs, related genes and corresponding selection strategies

Strategies SNPs Related Genes
The expression levels of mRNAs associated with SNPs using eQTL analysis(P < E-05)

107 SNPs

(see Additional file 1: Table S4)

-
The 5 SNPs with smallest p values rs7203246 EEF2K
rs62292160 ADRA2C
rs17170200 TPK1
rs2189164 TACR3
rs3786247 LIPG
Related genes were involved in the modulation of immune functions or playing a role TB rs1667908 MBP
rs7203246 EEF2K
rs12712986 TTC7A
Related genes interact in a regulatory network rs4654400 PTPRU
rs7203246 EEF2K
rs62292160 ADRA2C
rs2189164 TACR3
rs3786247 LIPG
rs1667908 MBP
rs17170200 TPK1

The table showed the strategy for screening the SNPs. First, 107 SNPs whose P value < E−05 were selected. In these 107 SNPs, the most differentially expressing 5 SNPs were selected, whose p value was less than E−07. 3 SNPs which played key roles in immune regulation or TB and 7 SNPs involved in the interaction network were select