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. 2021 Jan 19;13:7. doi: 10.1186/s13098-021-00625-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Exosomes derived from LPS-induced HK2 cells mediated the release of circ-FANCA. a Electron micrograph of exosomes isolated from the culture medium of LPS-treated HK2 cells or untreated HK2 cells. The scale bar represents 100 nm. b Western blot analysis for exosome markers (CD9 and CD63) in HK2 cells. c QRT-PCR assay for the expression level of exo-circ-FANCA in HK2 cells treated with LPS. d QRT-PCR assay for the expression of circ-FANCA in HK2 cells co-incubated with exosomes derived from LPS-induced HK2 cells or PBS. e QRT-PCR assay for the expression of exo-circ-FANCA in LPS-treated HK2 cells co-incubated with GW4869 or not. **P < 0.01, ***P < 0.001, ****P < 0.0001