Table 1.

MULTI-seq and SCMK classification performance summary

Method	MULTI-seq	SCMK
% Unclassified (deMULTIplex)	1.5%	36.2%
% Unclassified (demuxEM)	2.8%	35.4%
% souporcell Donor Match (deMULTIplex)	99.9%	99.0%
% souporcell Donor Match (demuxEM)	98.8%	97.7%

Classification performance was determined using two statistics: (i) % Unclassified, proportion of cells classified into donor groups by souporcell that remain unclassified by MULTI-seq or SCMK; (ii) % Donor Match, proportion of cells classified into the same donor group by MULTI-seq or SCMK and souporcell. Both metrics were computed using results from both deMULTIplex and demuxEM